CSF3 and lymphoma: On day 8 in the lymphoma model, the IL-12 post-only treatment groups yielded a significant rise in platelet counts as compared to the vehicle control (p < 0.05) Also as compared to G-CSF on day 8, the IL-12 post-only and pre-post treatment groups produced a statistically significant rise in platelets (p < 0.001) in the EL4 model.