This is particularly remarkable for the IL-12 pre-only treatment group where the rise in platelet counts in the lung cancer model occurred at a dose of only 50 ng, which is 1/30 of the dose of G-CSF (1.5 μg) on a weight basis (and less than 1/100 of the dose of G-CSF on a molar basis). This evidence concerns the gene CSF3 and lung cancer.