Interestingly, proteins belonging to signalling pathways not chosen to 'anchor' the analysis (such as IMD (= Immune Deficiency) and JNK (= Jun N-terminal kinase)) are classified within signalling modules defined by the 'anchoring' pathways (TGF1 and TOL2 for IMD, HH2 EGFR and TOR RAS2 for JNK). The gene discussed is RORC; the disease is Immunodeficiency.