Figure 4 shows the distribution of CD8+ Tcell subsets by flow cytometry (a) and changes in the proportion of CD8+ T cell subsets (b) as well as IFN-γ, perforin, and CD27−CD28− subsets (c) after LDLT in a representative of Group I recipient (53-year-oldfemale) undergoing LDLT to treat HCV-related liver cirrhosis. The gene discussed is PRF1; the disease is cirrhosis of liver.