These include age, body mass index (BMI), smoking, SBP and diastolic blood pressure (DBP), fasting plasma cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, C-reactive protein (CRP), homocysteine, lipoprotein (a) (Lp(a)), fibrinogen, hypertension, and diabetes. The gene discussed is CRP; the disease is diabetes mellitus.