NCR3 and neoplasm: While both NKp30-Ig and NKp46D2-Ig showed specific and similar levels of binding to PC3/Luc and DU145 cell lines in vitro, treatment of mice with NKp46D2-Ig did not induce any therapeutic effect and no inhibition of tumor growth was observed in either the PC3/Luc or the DU145 xenografts.