Besides flbroblaststhe cyst wall contained numerous polymorphonuclear leukocytes whichwere positively stained for cathespin G. α2-macroglobulin,α1-inhtbitor-3, α1-proteinase inhibitor, albumin and C3 weremeasured by electroimmunoassay and all showed plasma concentrationpatterns that were dose-dependent to the amount of interleuktn-1βreleased. This evidence concerns the gene C3 and cyst.