SRCIN1 and neoplasm: However, unfavourable associations between p130Cas expression and breast cancer recurrence and resistance to tamoxifen (van der Flier et al, 2000, 2001) and our identification (as described here) of SNIP/p140Cap in breast tumours – but not in normal breast tissue – and its association with larger tumours and shorter survival times from diagnosis, suggest that its effects may, at least in part, be due to an involvement with p130Cas.