To investigate whether this had any effect on the entry of SFV, the T-REx-nsP1, T-REx-nsP16D and HEK293 T-REx cells were infected with virus-like particles (VLPs) containing packaged SFV1-d1EGFP replicons, capable of infection and d1EGFP expression, but unable to produce infectious progeny (Žusinaite et al., 2007). This evidence concerns the gene SH2D3A and infection.