Cellularity (p = 0.01), mitosis (p < 0.001), tumour size (p = 0.01), high risk (p = 0.01), Ki67 (p = 0.02), and p27Kip1 (p = 0.05) were significantly associated with reduced relapse free survival (RFS), by univariate analysis, as showed in Table 4. This evidence concerns the gene CDKN1B and neoplasm.