The secretion of tumour necrosis factor-α (TNFα),interleukin-1α (IL-α) and interleukin-6 (IL-6) by ahuman astrocytoma cell fine was studied 1 h, 3 h, 6 h and 24 h afterinfection with tachyzoites from three Toxoplasma gondiistrains (virulent, RH; cystogentc, 76K and Prugniaud strains). This evidence concerns the gene TNFRSF9 and astrocytoma (excluding glioblastoma).