In order to investigate whether the cellular uptake of the complexes was mediated byapotransferrin or transferrin, we compared the antiproliferative efficacy ofHInd[RuInd2Cl4] and HIm[RuIm2Cl4] with its apotransferrin- and transferrin-bound formin the human colon cancer cell line SW707 using the microculture tetrazolium test (MTT). The gene discussed is TF; the disease is malignant colon neoplasm.