FXN and Friedreich ataxia: In a previous study, a substantial increase in frataxin in lymphoblastoid cells and in primary, non-replicating lymphocytes from FRDA patients was only obtained when using a specific class of HDACI, analogs of the compound BML-210 (N1-(2-aminophenyl)-N8-phenyloctanediamide), including the highly active compound 4b (N1-(2-aminophenyl)-N7-phenylheptanediamide) [22].