Subsequently, GWA studies in Finnish, English, Icelandic and Danish populations emphasized the role of CDKAL1, CDKN2A/2B and IGFBP2 on T2D and confirmed the effect of TCF7L2, SLC30A8 and HHEX[2]–[5]. The gene discussed is IGFBP2; the disease is type 2 diabetes mellitus.