TIMP-1 and TIMP-2 have been measured as controls in 2 studies (373 ng/mL and 106 ng/mL).34,35 TIMP-1 level has been shown to be higher in patients with pressure ulcers characterized as “good healers” (170 ng/mL)36 than “poor healers” (56 ng/mL).36 TIMP-1 level is much higher in wound drainage when negative pressure wound therapy is used (1493 ng/mL),37 perhaps related again to stimulation by foreign body. Here, TIMP1 is linked to decubitus ulcer.