The immunohistochemical stains for melanoma (S100, tyrosinase, Melan A and HMB-45), carcinoma (CK), gastrointestinal stromal tumours (CD-34, vimentin and c-Kit) and lymphoma (LCA) were performed with negative results, except for a weak and focal expression of vimentin. The gene discussed is TYR; the disease is melanoma.