The average expression level of RGS4 mRNA in this cohort measured by relative real-time PCR was previously reported [31] to be down-regulated by -2.06 fold (p = 0.03, df = 12, t = -2.33) in the schizophrenia subjects compared to the controls and there was no significant correlation of altered RGS4 expression and age (R2 = 0.27, p = 0.18), brain pH (R2 = 0.20, p = 0.32) or PMI (R2 = 0.15, p = 0.46). This evidence concerns the gene RGS4 and schizophrenia.