We found higher expression levels in MM for several genes implicated or known as melanoma-associated tumor antigens (MAGE, CSAG2) and some genes previously implicated in melanoma progression (GDF15, MMP14, SPP-1), cell cycle progression (CDK2, TYMS, BUB1) and the prevention of apoptosis (BIRC5, BCL2A1). This evidence concerns the gene SPP1 and Miyoshi myopathy.