Two multi-locus models exhibited significant association with AD in the ADm vs. Cm comparison: lhcgr2/APOE (8 of 10 CVs, >0.5 training accuracy in 7 of 10 CVs) and lhcgr2/lhcgr5/APOE (7 of 10 CVs, >0.5 training accuracy in 9 of 10 CVs). Here, APOE is linked to Alzheimer disease.