HLA-DRB1 and systemic lupus erythematosus: In 2002, a family-based association study [51] identified three microsatellite-inferred risk haplotypes in European lupus families: DRB1*1501/DQB1*0602, DRB1*0301/DQB1*0201, and DRB1*0801/DQB1*0402.