Diabetes mellitus is a metabolic disorderresulting from the permanent lack of insulin production from the pancreas (type1 diabetes) or the chronic degradation of the functionality of endogenousinsulin (type 2 diabetes), which results in raising the glucose concentrationin blood because without insulin, the cellular system cannot properly convertcarbohydrates such as sugars, starches, or other foods into energy usable by thebody. The gene discussed is INS; the disease is type 2 diabetes mellitus.