The results of logistic regression analyses (Table 3) suggest that the heterozygous genotype of ACE(ins/del) and ADRB2(gln27glu) and the homozygous genotype of the AA allele of APOC3 (C-641A) may predict disturbed glucose metabolism (i.e. subjects who were IGM or who had T2DM; P = 0.001, P = 0.002 and P = 0.008, respectively). Here, ACE is linked to type 2 diabetes mellitus.