Recently Alazami et al., (2006) [41] have corroborated the earlier findings of Marcelino et al., (1999) [42] demonstrating that camptodactyly-arthropathy-coxavara-pericarditis (CACP) syndrome (where one or more fingers are curved inwards on the palm (flexed) and cannot be straightened) is an autosomal recessive disorder caused by mutations in the PRG4 gene. Here, PRG4 is linked to Camptodactyly.