The finding that serum/glucocorticoid regulated kinase (SGK) message is downregulated in DC fibroblasts is contrary to previous studies that document a high level of expression of SGK transcript in fibrosing disorders such as Crohn's disease, fibrosing pancreatitis, diabetic nephropathy, lung fibrosis and liver scirrhosis [53]. Here, SGK1 is linked to diabetic kidney disease.