In a recent paper, den Hollander et al. were able to predict the involvement of TULP1 based on the disease phenotype, which they believed is specific for TULP1. This phenotype included early-onset nyctalopia with nystagmus; relative preservation of the isopters on kinetic perimetry, despite poor visual acuity; and a perifoveal yellow annular ring [16]. The gene discussed is TULP1; the disease is Nystagmus.