The total number of CD45+ tumor infiltrating immune cells increased 10 d after intratumoral delivery of Ad-Flt3L and Ad-TK (p<0.001, Fig. 7 C), as did the numbers of CD4+ T cells (p<0.001, Fig. 7 D) and CD8a+ T cells (p<0.001, Fig. 7 E). Here, CD4 is linked to neoplasm.