For example, Tang and colleagues studied 140 breast tumors and found an association between high nuclear Bag-1 expression and decreased survival [58], Townsend and colleagues found no significant association between nuclear or cytoplasmic Bag-1 and survival in 160 patients [59], and Turner and colleagues found a strong association between high cytoplasmic Bag-1 and improved survival [60]. The gene discussed is BAG1; the disease is breast neoplasm.