To further detail the features of the adaptive immune responses observed in LM we designed qPCR primers for well-known genes of humoral (IgM, -Z and -D heavy chain) and T-cell mediated (CD8+ CTL response; CD8α, CD4+ TH1 response; IFN-γ and TH2 response; TGF-β) immunity. The gene discussed is CD4; the disease is lymphangioma.