IGHE and infection: In the population where mRNA expression was analyzed (see Materials and Methods), 14 out of 74 schistosome negative children had a positive skin reaction to mite (19%), whereas 5 out of 46 schistosome-infected children were SPT positive for mite (11%) resulting in a significant negative association between infection with S. haematobium and atopy (OR 0.26 [0.07–1.00], p = 0.05, adjusted for age, sex, school and levels of mite IgE).