The selected transcripts involved in diabetes included PRF1, HLA-DQA1, HLA-DQB1, SOCS3, HLA-DPA1, and GZM2. We also saw significant differences in transcripts involved in the nervous system (e.g., MATK, NCAM1, GPR56, MEF2C, ZFHX1B) and other aspects of development (e.g., AES, TAGLN, ARIH2, WNT10A, MRAS, ITGA6, ANXA2, VAMP5) [Supplemental Material, Table 1 (http://www.ehponline.org/members/2008/10861/suppl.pdf]. This evidence concerns the gene TLE5 and diabetes mellitus.