The selected transcripts involved in diabetes included PRF1, HLA-DQA1, HLA-DQB1, SOCS3, HLA-DPA1, and GZM2. We also saw significant differences in transcripts involved in the nervous system (e.g., MATK, NCAM1, GPR56, MEF2C, ZFHX1B) and other aspects of development (e.g., AES, TAGLN, ARIH2, WNT10A, MRAS, ITGA6, ANXA2, VAMP5) [Supplemental Material, Table 1 (http://www.ehponline.org/members/2008/10861/suppl.pdf]. The gene discussed is PRF1; the disease is diabetes mellitus.