Synthetic molecules (glitazone molecules, which bind to PPARα, or glitazar molecules, which bind to PPARα/PPARγ), currently being tested in clinical studies, may prove particularly useful for the treatment of certain types of infertility associated with metabolism disorders such as insulinoresistance in polycystic ovary syndrome (PCOS) [8]. The gene discussed is PPARA; the disease is polycystic ovary syndrome.