PPARG and Insulin resistance: The association of the PPARG Pro12Ala polymorphism with metabolic traits and the risk/development of DM hasbeen investigated in individuals of all ages and of different ethnicities includingChinese and Japanese individuals in the Hypertension and Insulin Resistance(SAPPHIRe) study, [76], Iranianindividuals [77], obeseItalian children, [78]middle-aged and elderly Finns, [75] and Spanish women [79].