In contrast, the current study found associations of various other inflammatory genes with adverse outcomes and it showed that at least for some part these associations could be clustered to members of the NF-κB pathway: TNFA and TNFR1 were highly associated with pleural effusion (odds ratios 118.3±59.6 and 31.4±15.9, respectively) and NFKB1 and TNFR1 correlated with hemorrhagic manifestations (odds ratios 14.0±6.4 and 14.0±6.9, respectively). The gene discussed is TNFRSF1A; the disease is Pleural effusion.