Not surprisingly, salient events in red (high AFI) with high amplitude and recurrence (high ARI) coincide with known common, high-amplitude and focal CNAs in GBM, including EGFR, PDGFRA, MET, PTEN, and CDKN2A/B (p16INK4A/p15INK4B). This evidence concerns the gene PTEN and glioblastoma.