Forty-four per cent of PCPs agreed that the risk of hypoglycaemia would make them reluctant to prescribe insulin for most patients ≥ 85 years old (item 1), 44% disagreed that most patients on oral diabetes therapy would be less adherent with insulin therapy, and 45% disagreed that they should wait until patients on oral therapy have a beta cell inadequacy to prescribe insulin (items 9, 10). The gene discussed is INS; the disease is diabetes mellitus.