IL6 and Fever: Perhaps safe conclusions can be drawn only forIL-6 for two main reasons: (a) monocyte stimulation with patients’ serum yieldedfurther release of IL-6 only for monocytes isolated within the first 12 hours fromadvent of fever (Figure 2), and (b) there is a negative correlation between timelapsing from start of fever and serum-stimulated release of IL-6 by monocytes(Figure 3).