MPO was measured inbaseline samples of a case-control study nested in the prospective EPIC-Norfolkpopulation study: case subjects (n = 1138) were apparently healthy men and womenwho developed CAD during 8 years of follow-up; control subjects (n = 2237)matched for age, gender, and enrollment time, remained free of CAD. Here, MPO is linked to coronary artery disorder.