In our dataset, survival analyses support prognostic roles for several differentially regulated transcripts, including RECQL4, FRRS1, CFH, ADAMTS9, MNAB, and to a lesser extent MET, SOX4, NA[1562932_at] and hypothetical protein FLJ10292. Interestingly, the combined prognostic effect of selected genes RECQL4, FRRS1, CFH and MET, as tested using a simple equal-weighted scoring system, was greater than that of tumour grade, our current best prognostic test. The gene discussed is SOX4; the disease is neoplasm.