In addition, studies in other cancer types such as testis [39], liver [40], colon [41], and pancreas [42] revealed over-expression of HSPC111. Interestingly, some but not all of these studies showed a concurrent over-expression of MYC [37,39], suggesting that HSPC111 is regulated both by Myc-dependent and -independent pathways. This evidence concerns the gene MYC and cancer.