MAPT and early-onset autosomal dominant Alzheimer disease: Abbreviations: CERAD = The Consortium to Establish a Registry for Alzheimer's disease; NP = neuritic plaques; NFT = neurofibrillary tangles; NIA‐RI = The national institute on Aging and Reagan Institute working group; NT = neuropil threads; IHC = immunohistochemistry; HP‐tau = hyperphosphorylated tau.