CD4 and infection: We found that, relative to the rest of the study participants, individuals infected with the T242N/A146X mutants had significantly lower viral loads and higher CD4+ counts at three months post-infection (median log VL 4.53 vs. 5.09, p = 0.0077 and median CD4+ count 652.0 vs. 460.0, p = 0.0129), (Figure 6a and b).