Median plasma MMP1 levels were significantly higher (p = 0.0005) in healthy controls (3.45 ng/ml, interquartile range IQR 2.42–4.17 ng/ml) than in breast cancer patients (2.01 ng/ml, IQR 0.79 – 3.71 ng/ml). This evidence concerns the gene MMP1 and breast carcinoma.