Yanxiaochu [97] et al detected cell proliferating degree in 54 cases of adrenocortical normal tissues, hyperplasia, adenoma and carcinoma by DNA Content, Ag-NOR, PCNA staining, and found that there was no difference between adrenocortical normal tissues and hyperplasia on DNA Content, Ag-NOR, PCNA Index (P>0.05). This evidence concerns the gene PCNA and adenoma.