4) It was found by Logistic Regression that 8 factors were likely linked to the diagnosis of hypercortisolism of adrenocortical diseases including FHIT, Ki-67, PCNA, abdominal mass, tumor size, decrease in bone content or fracture, blood cortisol level (4PM), blood ACTH level (8AM) amongst which FHIT and PCNA are the most imprtant features for diagnosis. This evidence concerns the gene MKI67 and neoplasm.