POMC and neoplasm: 4) It was found by Logistic Regression that 8 factors were likely linked to the diagnosis of hypercortisolism of adrenocortical diseases including FHIT, Ki-67, PCNA, abdominal mass, tumor size, decrease in bone content or fracture, blood cortisol level (4PM), blood ACTH level (8AM) amongst which FHIT and PCNA are the most imprtant features for diagnosis.