A recent study by Rossi et al regarding immunocytochemical stains evaluation of thyroid neoplasms on TP slides from thyroid FNAB revealed that combining the cytomorphology with the immunocytochemical stain panel of HBME-1, Galectin-3 and RET was effective in distinguishing follicular lesions requiring surgery from those lesions requiring only follow-up [24]. This evidence concerns the gene RET and thyroid gland disorder.