While the stimulation of transcription and increased occupancy of the late coding region at 48 hours post-infection following treatment correlates very well with a marked increase in hyperacetylated histones which we previously observed following NaBu treatment [12], it is also possible that the effects of treatment at 48 hours post-infection or other times is a result of an indirect effect of the HDAC inhibitors. The gene discussed is HDAC9; the disease is infection.