Among the HNSCC-derived cell lines used in our previous report (Canel et al, 2006), we have selected SCC40 and SCC38 cells as systems to study the phenotypic effects of inhibiting FAK, because they express high levels of FAK and the predominant location of activated FAK (pTyr397-FAK) is at focal adhesion sites. Here, PTK2 is linked to head and neck squamous cell carcinoma.