In addition, male BRCA1 and (to a greater extent) BRCA2 carriers are at an increased risk of developing breast cancer (Thorlacius et al, 1997; Thompson and Easton, 2001; Risch et al, 2006; Tai et al, 2007), (DF Easton, unpublished data). Here, BRCA1 is linked to breast carcinoma.