AKT1 and prostate neoplasm: Prostate tumours are reported to have significantly higher Akt expression than BPH (Liao et al, 2003), and only 10% of well-differentiated prostate tumours strongly express pAkt compared to 92% of poorly differentiated tumours (Malik et al, 2002; Ayala et al, 2003; Ghosh et al, 2003).