Since specific anti-EpoR antibodies have yet to be identified, we investigated if EpoR was overexpressed in tumours by performing a systematic analysis of EPOR genomic amplification and transcription in more than 15 different primary tumour types, and EpoR transcript and surface EpoR expression analysis in representative tumour cell lines in which rHuEpo has been reported to induce responses (Westenfelder and Baranowski, 2000; Acs et al, 2001, 2003; Pajonk et al, 2004; Um et al, 2007). Here, EPOR is linked to neoplasm.