CKB and cancer: Because we do see CK-B in filopodia and phagocytic cups in our RAW cells (Figures 1G–1L and 4), but also observe CK-B accumulation in dynamic actin structures of other cell types during adhesion to substratum, spreading, and crawling, (e.g., in neurons and astrocytes; unpublished data), this raises the exciting possibility that CK-B facilitates rapid cytoskeletal dynamics in a broad range of specialized events that occur during tissue development and disease, including dendritic spine generation in brain [65], formation of immune-synapses, or protrusion dynamics for cancer cell invasion.