Instead, we examined the expression of IFN-α signature genes in SLE PBMCs [32], including IFIT1 (IFN-induced protein with tetratricopeptide repeats 1), IFI44 (IFN-induced protein 44), and PRKR (IFN-inducible double-stranded RNA-dependent protein kinase). The gene discussed is IFIT1; the disease is systemic lupus erythematosus.