As expected from results presented in Figures 1b and 2b, the relative IFN-α producing capacity of pDCs was significantly lower in SLE patients than in control individuals (0.2 ± 0.18 in SLE patients versus 1 ± 0.5 in control individuals; P < 0.01; Figure 2c). The gene discussed is IFNA1; the disease is systemic lupus erythematosus.