In particular, OPGlevels were independently associated with cardiovascular mortality, but notbone mineral density in patients suffering from cerebrovascular diseases [109].Furthermore, OPG is correlated with significant coronary artery narrowing [110].Interestingly, osteoprotegerin gene polymorphisms were shown in coronary arterydisease in Caucasian men [111]. Here, TNFRSF11B is linked to cerebrovascular disorder.